KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1A
All Species:
13.64
Human Site:
S490
Identified Species:
27.27
UniProt:
Q6PJP8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJP8
NP_055696.3
1040
116422
S490
Q
N
T
I
R
K
L
S
S
E
N
L
N
A
K
Chimpanzee
Pan troglodytes
XP_508045
1040
116405
S490
Q
N
T
I
R
K
L
S
S
E
N
L
N
A
K
Rhesus Macaque
Macaca mulatta
XP_001090942
1039
116662
S490
Q
S
K
I
R
K
L
S
S
E
N
L
N
A
K
Dog
Lupus familis
XP_535018
1074
119811
S524
Q
S
K
I
R
K
L
S
S
K
N
F
S
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIC3
1026
113549
G479
S
K
P
L
E
K
E
G
G
K
C
L
P
L
H
Rat
Rattus norvegicus
NP_001099671
1026
112807
E476
M
S
K
P
L
E
K
E
G
G
E
R
L
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513453
994
111830
E464
S
L
P
L
K
S
T
E
R
E
V
L
E
L
S
Chicken
Gallus gallus
Q5QJC4
972
108310
Q442
Y
S
C
L
T
R
T
Q
S
L
L
L
T
E
G
Frog
Xenopus laevis
NP_001093331
932
103215
I403
C
S
S
P
A
P
E
I
G
E
W
D
T
Y
Q
Zebra Danio
Brachydanio rerio
XP_002664006
926
102909
S397
S
Q
L
Q
S
P
Q
S
L
V
L
E
H
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321063
382
43088
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38961
484
55143
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
93.5
71.6
N.A.
62.8
61.8
N.A.
49.7
43.4
40.2
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
96
78.9
N.A.
72.5
72.5
N.A.
63.3
58.2
55.4
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
66.6
N.A.
13.3
0
N.A.
13.3
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
26.6
13.3
N.A.
26.6
33.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.6
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
27.1
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
34
0
% A
% Cys:
9
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
9
9
17
17
0
42
9
9
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
25
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% H
% Ile:
0
0
0
34
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
25
0
9
42
9
0
0
17
0
0
0
0
34
% K
% Leu:
0
9
9
25
9
0
34
0
9
9
17
50
9
25
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
0
34
0
25
0
0
% N
% Pro:
0
0
17
17
0
17
0
0
0
0
0
0
9
9
0
% P
% Gln:
34
9
0
9
0
0
9
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
34
9
0
0
9
0
0
9
0
0
9
% R
% Ser:
25
42
9
0
9
9
0
42
42
0
0
0
9
0
9
% S
% Thr:
0
0
17
0
9
0
17
0
0
0
0
0
17
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _